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Capto MMC, 25 mL , Cytiva (CAT#: STEM-C-1561-LC)

Highlights

Multimodal cation exchanger with a different selectivity than traditional ion exchangers
High dynamic binding capacity at high conductivity increases productivity
High-volume throughput cuts process times

Cat Number: STEM-C-1561-LC

Application: Used to bind proteins at the conductivity of the feed material

Model: 17-5317-10

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Description

Capto MMC manufactured by Cytiva is a multimodal weak cation exchanger that is salt-tolerant and features a different selectivity, compared with traditional ion exchangers.
Capto MMC combines agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. This resin can be used to bind proteins at the conductivity of the feed material. It can also be used to solve specific purification challenges at both high and low ionic strengths.

Specification

BioProcess resin: Yes
Particle size, d50V1: ~75 µm
Ion Exchanger Type: Multimodal weak cation exchanger
Matrix: Highly cross-linked agarose
Binding Capacity/ml Chromatography Medium2:> 45 mg BSA/mL resin at 30 mS/cm
Ionic Capacity: 0.07-0.09 mmol H+/ml medium
pH stability, operational3: 2-12
pH stability, CIP4: 2-14
Pressure/Flow Specification: 300 kPa at 600 cm/h, 1 m diameter column, 20 cm bed height
Storage: 4 to 30°C, 20% Ethanol
Chemical stability5: Commonly used aqueous buffers, 1 M acetic acid, 1 M sodium hydroxide, 8 M urea, 6 M guanidine hydrochloride, and 70% ethanol
Pack size: 25 mL

Features

Multimodal cation exchanger with a different selectivity than traditional ion exchangers
High dynamic binding capacity at high conductivity increases productivity
High-volume throughput cuts process times
Smaller unit operations give cost-effective processing and reduce investments
Meets industrial demands for security of supply, robust performance, and regulatory support
An alternative solution to traditional ion exchangers

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