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The endocrine system, made up of all the body's different hormones, regulates all biological processes in the body from conception through adulthood and into old age, including the development of the brain and nervous system, the growth and function of the reproductive system, as well as the metabolism and blood sugar levels. The female ovaries, male testes, and pituitary, thyroid, and adrenal glands are major constituents of the endocrine system. Endocrine diseases are disorders of the endocrine system. Endocrine disorders are often quite complex, involving a mixed picture of hyposecretion and hypersecretion because of the feedback mechanisms involved in the endocrine system.