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Animal disease models are mainly used in experimental physiology, experimental pathology and experimental therapeutics (including new drug screening) research. Indirect research with the help of animal models can consciously change those factors that are impossible or not easy to exclude under natural conditions, so as to more accurately observe the experimental results of the models and carry out comparative research with human diseases, which will help to more conveniently and effectively recognize the developmental laws of human diseases and study preventive and curative measures. Common five-sense disease include diseases of the ear, nose, throat, pharynx, eye, and teeth.