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Microfluidic chip integrates basic operation units such as sample preparation, reaction, separation and detection in biological, chemical and medical analysis processes into a micron-scale chip to automatically complete the whole process of analysis, which is the main platform for microfluidic technology realization. Microfluidic chips have the advantages of controllable liquid flow, few samples and reagents consumed, and fast analysis speed, which are the hot fields in the development of miniaturized total analysis systems. Microfluidic chips are widely used in biological research, drug analysis, medical diagnosis and other fields.