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Animal disease models are non-human animals bearing pathologies that share features with a human disease. Disease models can either exist naturally or be induced artificially and are used for studying human disease with an experimental system. With a shorter life cycle than humans, animal models can be studied throughout their whole life span and across several generations, a critical element in understanding how a disease processes and how it interacts with a whole, living biological system. Animal research is considered a key element in advance of biomedical science. The contribution of animal models in medicine is essential for understanding the physiopathology and novel treatment alternatives for several animal and human diseases