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Chemokines are a class of small molecular cytokines with similar primary structure, which can chemotactic cells to move in a targeted manner. They play a wide range of physiological and pathological roles in the development of immune cells and organs, immune response process, inflammatory response, pathogen infection, wound repair, tumor formation and metastasis. According to the position and number of N-terminal cysteine residues, chemokines can be divided into 4 sub-families: CC, CXC, XC and CX3C.