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Chronic Bronchitis Animal Model (CAT#: STEM-AE-0058-WXH)

Introduction

Chronic bronchitis refers to the chronic non-specific inflammatory response of the trachea, bronchial mucosa and surrounding tissues caused by infection or non-infection factors. The pathological features of chronic bronchitis are bronchial gland hyperplasia and increased mucus secretion. Clinically, it is often characterized by repeated attacks of cough, sputum or wheezing, each lasting for more than 3 months and more than 2 years in a row. In severe cases, it may be complicated by obstructive emphysema or even cor pulmonale.




Applications

• Study the pathogenesis and treatment of chronic bronchitis.
• Drug development, drug screening and efficacy research.

Procedure

• Chemical drug method (sulfur dioxide, chlorine, ammonia water, lipopolysaccharide, enzymes, adrenergic drugs, cholinergic drugs, secretagogues, etc.)
• Bacterial infection method (Streptococcus pneumoniae, etc.)
• Passive smoking method and compound method (such as bacteria plus smoke, bacteria plus cold, etc.).
These methods can be used alone or in combination.

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