COSY and NOESY Spectroscopy Service for Conformational Analysis Based on 500 MHz Spectrometer

STEMart offers COSY (Correlation Spectroscopy) and NOESY (Nuclear Overhauser Effect Spectroscopy) services for conformational analysis, utilizing our advanced 500 MHz spectrometers, including the Bruker Avance III HD 500 MHz and JEOL ECZ500R 500 MHz systems. These instruments are essential tools in our laboratory, enabling high-resolution two-dimensional NMR studies that reveal structural and spatial relationships between nuclei in molecules. Our COSY and NOESY spectroscopy services support researchers in structural biology, organic chemistry, and pharmaceutical sciences by providing precise data on molecular conformations and spatial orientations.

COSY and NOESY spectroscopy are powerful techniques for analyzing molecular structures. COSY reveals through-bond interactions between neighboring nuclei, offering insights into connectivity and bonding patterns. NOESY, on the other hand, detects through-space interactions, providing valuable information on the spatial proximity of atoms within a molecule. Together, these techniques allow for comprehensive conformational analysis, widely applied in the study of complex molecules, including proteins, nucleic acids, and pharmaceuticals.

Leveraging our 500 MHz spectrometers and extensive expertise, STEMart offers a full suite of conformational analysis services, including bond connectivity studies, spatial orientation determination, and conformational mapping. Our services provide researchers with the accurate and detailed data needed to understand molecular structures and dynamics, essential for advancing research and development in structural biology and chemistry.

What We Offer

• Bond Connectivity Analysis via COSY

Utilizes COSY spectroscopy to map through-bond interactions, revealing connectivity patterns and supporting molecular structure elucidation.

• Spatial Proximity Detection via NOESY

Uses NOESY spectroscopy to detect through-space interactions, providing valuable insights into spatial arrangement and conformational relationships.

• Conformational Mapping of Complex Molecules

Analyzes molecular conformations to study the structure and orientation of complex molecules, aiding in fields like drug discovery and structural biology.

• Stereochemical Analysis

Provides insights into stereochemistry, helping to distinguish between different stereoisomers and supporting research in chiral molecule development.

Why Choose Us

• High Resolution for Detailed Structural Analysis

Our 500 MHz spectrometers provide high resolution, enabling precise conformational studies and supporting accurate structure determination.

• Experienced Team in Structural NMR

Our NMR specialists have extensive expertise in COSY and NOESY, ensuring accurate interpretation and high-quality results for complex analyses.

• Non-Destructive Testing

Our NMR-based methods preserve samples, allowing for further analysis or testing if needed, especially useful for valuable or limited samples.

• Flexible Reporting for Targeted Insights

We provide customizable reports tailored to specific research needs, ensuring clarity and value in data presentation.

Our Resources

Bruker Avance III HD 500 MHz NMR

The Bruker Avance III HD 500 MHz spectrometer features advanced capabilities for COSY and NOESY spectroscopy, providing high-resolution data on molecular connectivity and spatial relationships, ideal for structural and conformational studies.

JEOL ECZ500R 500 MHz NMR

This JEOL 500 MHz system is designed for high-precision two-dimensional NMR, offering robust performance for COSY and NOESY analyses. Its sensitivity and stability make it an invaluable tool for studying complex molecular conformations and spatial arrangements.

STEMart provides high-quality NMR services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our NMR services and how we can help you achieve your research goals.