Critical Micelle Concentration (CMC) Determination

STEMart offers a cutting-edge CMC determination service designed to measure surfactant self-assembly with unparalleled precision. Our laboratory is equipped with state-of-the-art instruments, specifically optimized for surfactant and amphiphilic compound analysis. These instruments enhance measurement accuracy while improving operational efficiency. Featuring automated systems and advanced software, they provide superior sensitivity, repeatability, and speed, ensuring high-quality results for our clients.

Critical Micelle Concentration (CMC)

CMC is a key physicochemical parameter that defines the concentration at which surfactant molecules spontaneously form micelles in a solution. Accurate CMC determination is essential for understanding the self-assembly behavior, solubilization capacity, and interfacial properties of surfactants and amphiphilic compounds. Our advanced analytical services provide precise and reliable CMC measurements to support formulation development, colloidal stability assessment, and pharmaceutical research.

Illustration of critical micelle concentration (CMC) (STEMart Authorized) Fig.1 Critical Micelle Concentration (CMC).

With extensive experience in surfactant characterization and pharmaceutical analysis, our expert team offers advanced methodologies for CMC determination, ensuring high precision and reproducibility. We provide customized solutions tailored to specific research and formulation requirements.

Analytical Techniques

Technology	Principle
Fluorescence Spectroscopy	Utilizing fluorescent probes such as pyrene or Nile Red to detect micelle formation onset.
Dynamic Light Scattering (DLS)	Measuring hydrodynamic size changes as a function of surfactant concentration to identify the micelle formation threshold.
Surface Tension Analysis	Monitoring interfacial tension changes to determine the CMC of surfactants.
Conductivity Measurements	Detecting changes in electrical conductivity associated with micelle formation.
Isothermal Titration Calorimetry (ITC)	Evaluating thermodynamic parameters related to micelle formation.

Regulatory Compliance

Our CMC determination services comply with industry standards and regulatory guidelines, ensuring reliable and reproducible results for pharmaceutical R&D and quality control. We adhere to ICH Q6B, USP, and EMA recommendations for surfactant characterization.

Why Choose Us

Illustration of advantages of STEMART (STEMart Original)

State-of-the-Art Instrumentation: Equipped with cutting-edge analytical tools for precise CMC determination.
Expert Scientific Team: Experienced professionals with deep expertise in surfactant and pharmaceutical analysis.
Customized Analytical Solutions: Tailored testing protocols to meet specific research and formulation needs.
Comprehensive Data Reporting: Delivering detailed analysis, graphical representations, and interpretation of results.

For more information on our Critical Micelle Concentration (CMC) Determination services or to discuss your specific requirements, please contact us today.

Critical Micelle Concentration (CMC) Determination