Cryo-ET for Biological Samples Based on JEOL CryoARM 300

STEMart offers advanced Cryo-Electron Tomography (Cryo-ET) services for biological samples using the JEOL CryoARM 300, a state-of-the-art cryo-electron microscope designed for high-resolution 3D imaging. The JEOL CryoARM 300 enables precise visualization of macromolecular complexes, organelles, and cells in their native environment, providing unparalleled insights into biological structures at the molecular level. Our laboratory is equipped with leading-edge instrumentation, ensuring that researchers receive accurate and reliable data for their structural biology projects.

The JEOL CryoARM 300 is specifically optimized for Cryo-ET, allowing for the reconstruction of 3D structures from multiple two-dimensional projections of frozen-hydrated samples. This technique preserves the biological specimens in their native state, avoiding the artifacts caused by traditional staining or fixation methods. Cryo-ET is widely applicable in fields such as virology, cell biology, and protein structural analysis, where high-resolution 3D data are essential for understanding biological processes.

Leveraging our JEOL CryoARM 300, STEMart provides comprehensive Cryo-ET services for biological samples, including sample vitrification, 3D reconstruction, and detailed structural analysis. Our expertise in cryo-electron microscopy ensures that your projects are supported with the highest level of precision and care, facilitating groundbreaking discoveries in structural biology.

What We Offer

• 3D Reconstruction of Macromolecular Complexes

Detailed 3D imaging and analysis of protein complexes, helping to reveal their functional and structural dynamics.

• Cellular and Organelle Structure Analysis

High-resolution tomography for visualizing the internal architecture of cells and organelles in their native state.

• Cryo-ET for Viral Particles

Structural studies of viral particles to aid in virology research, vaccine development, and antiviral drug discovery.

• Subcellular Cryo-Tomography

Advanced 3D imaging of subcellular components to understand their interactions and functional mechanisms.

Why Choose Us

• High-Resolution 3D Imaging

Our JEOL CryoARM 300 offers cutting-edge 3D reconstructions at the molecular level, providing detailed insights into biological structures.

• Native Sample Preservation

Cryo-ET preserves biological samples in their native environment, avoiding the need for traditional staining or chemical fixation.

• Comprehensive Workflow

We provide full support throughout the entire workflow, from sample preparation to 3D reconstruction and data analysis.

• Expertise in Structural Biology

Our team has extensive experience in cryo-electron microscopy, ensuring reliable results for your biological research.

Our Equipment

JEOL CryoARM 300 Cryo-Electron Microscope

The JEOL CryoARM 300 is a high-end cryo-electron microscope designed for advanced Cryo-ET applications. With a 300 kV electron source, direct electron detector, and automated data acquisition, it delivers high-resolution 3D reconstructions of biological samples. Its cryogenic sample holder ensures that specimens are maintained in their vitrified state, enabling accurate structural analysis of proteins, cells, and viruses. This instrument is a vital tool for researchers in structural biology and virology.

STEMart provides high-quality advanced microscopy services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our advanced microscopy services and how we can help you achieve your research goals.