De Novo Sequencing Service Based on High-Resolution MS

STEMart offers cutting-edge De Novo Sequencing Services using High-Resolution Mass Spectrometry (HRMS), a highly accurate and sensitive technology for determining the amino acid sequence of proteins and peptides. In our laboratory, HRMS plays a critical role in delivering precise, detailed de novo sequencing data, even for unknown or novel proteins where reference sequences are unavailable. This technology is essential for a wide range of disciplines, including proteomics, drug development, and biologics research, where sequence accuracy is vital for product development and innovation.

De novo sequencing with HRMS involves fragmenting peptides into smaller components and measuring the mass-to-charge ratios of these fragments. By using high-resolution mass spectrometry, STEMart can precisely identify even minor differences in mass, allowing for accurate sequencing of complex proteins and peptides. This technique is particularly useful for characterizing post-translational modifications, identifying unknown proteins, and verifying the sequence of therapeutic proteins and antibodies.

Leveraging the power of high-resolution mass spectrometry, STEMart offers comprehensive de novo sequencing services to support your research and development needs. Whether you are working with therapeutic proteins, unknown peptides, or complex biologics, our services provide the detailed sequencing data necessary to advance your project with confidence.

What We Offer

• Complete Protein Sequencing

We provide comprehensive de novo sequencing of proteins and peptides, offering accurate identification of amino acid sequences for both known and novel proteins.

• Post-Translational Modification (PTM) Analysis

Our service includes detailed analysis of PTMs, helping to identify modifications such as phosphorylation or glycosylation that may affect protein function.

• Antibody and Biologic Verification

We offer sequencing services for therapeutic antibodies and biologics, ensuring that the sequence matches the intended design and supporting quality control efforts.

Why Choose Us

• High Resolution and Precision

Our HRMS system delivers exceptional resolution and precision, ensuring accurate sequencing of even complex or modified proteins and peptides.

• Comprehensive Sequencing Solutions

We offer a wide range of de novo sequencing services, tailored to meet the needs of researchers in drug development, proteomics, and biologics research.

• Rapid Turnaround Time

Our efficient workflows allow us to deliver high-quality sequencing data quickly, helping you meet tight deadlines for research or product development.

Our Equipment

High-Resolution Mass Spectrometer (HRMS)

This advanced system provides accurate mass measurements and high-resolution detection, making it ideal for de novo sequencing and identification of proteins and peptides.

Triple Quadrupole MS

Complementing our HRMS, this system enhances peptide fragmentation analysis, offering detailed insights into amino acid sequences and post-translational modifications.

Nano-LC-MS/MS

This nano-scale liquid chromatography system improves sensitivity for sequencing low-abundance proteins and peptides, ensuring accurate results for challenging samples.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.