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Determination of Melting Point of Chalcones and Their Derivatives by Open Capillary Method (CAT#: STEM-PPA-0063-YJL)

Introduction

Materials have always been fundamental to technological advances whether it is electronics, photonics, sensors, medicine, energy or even weapons. In this regard study of light-matter interactions are important as they provide means to control different aspects of electromagnetic radiation which are crucial for many applications.
In the past two decades, chalcones and their derivatives have emerged as a promising class of NLO materials due to their peculiar structural aspects which allows for tunable NLO features. Basic structure of chalcones consists of an electron donor (D), acceptor (A) and a π-bridge in between. Strength of nonlinear absorption (NLA) depends on the length of the bridge, strength of the A and D moieties and nature of the surroundings such as polarity of the medium.




Principle

Melting point is a characteristic property of solid crystalline substance. It is the temperature at which the solid phase changes to the liquid phase. This phenomenon occurs when the substance is heated.
In all major pharmacopoeias the open capillary method is described to determine the melting point (slip point) for fats, fatty acids, paraffin, and waxes. In a glass capillary tube open at both ends (1), 10 mm of sample is introduced (2), chilled to a given temperature and immersed into a water bath (3/4). The melting point with open capillary, also known as slip point or slip melting point, is the temperature at which the substance begins to rise in the capillary due to the effect of the increasing temperature and buoyancy.

Applications

Chemical industry; Cosmetic/pharmaceutical industry

Procedure

1. Prepare the substance.
2. Affix one of the capillaries to a thermometer.
3. Place the thermometer with an affixed capillary into a glass.
4. Increase the temperature.

Materials

• Sample Type: crystalline compounds
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