Determination of Melting Point of Dihydropyrimidine by Open Capillary Method (CAT#: STEM-PPA-0065-YJL)

Introduction

In recent years dihydropyrimidines and its derivatives showed significant applications due to their pharmacological and therauptic properties. Compounds containing dihydropyrimidinecore unit shows biological activities such as antitubercular agent anti-inflammatory agents,antiviral,antibacterial, antimalarial, antihypertensive agents, cytotoxic, calciumchannel antagonists etc.
Numerous inorganic oxides such metal oxides have been reported to synthesis of various organic compounds and derivatives. They have been found to have better catalytic activities than the conventional type of catalyst and have wide applications in synthesis due to shorter reaction time such as in Bigenelli type reactions. dihydropyrimidine was synthesized using gadolinium oxide (Gd2O3) as a catalyst.