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The necessity to measure molecular weight and molecular weight distribution of polymers arises from the importance of molecular weight in controlling the mechanical properties of polymers and its large influence on manufacturing and processing. The methods used to determine molecular weight are numerous and include end group analysis; membrane osmometry; intrinsic viscosity; light scattering; size exclusion chromatography (SEC); colligative properties (e.g., ebulliometry, cryoscopy, and vapor pressure osmometry); and ultracentrifuge. They cover weights ranging from <10 × 103 (end group analysis method) to < 40 × 106 (Ultracentrifuge method).