Drosophila Cardiovascular Disease Model Service Based on Pacing-Induced Heart Failure Models

STEMart offers a cutting-edge Drosophila Cardiovascular Disease Model Service utilizing pacing-induced heart failure models to study heart disease mechanisms and evaluate potential therapeutic interventions. By leveraging advanced pacing techniques in Drosophila (fruit flies), we induce cardiac stress and heart failure, providing a powerful model for exploring cardiovascular diseases such as arrhythmias, cardiomyopathies, and heart failure. Our lab is equipped with state-of-the-art systems to precisely control heart pacing and monitor cardiac function, offering high-throughput and cost-effective solutions for preclinical cardiovascular research.

The pacing-induced heart failure model involves subjecting Drosophila to mechanical or electrical stimulation that accelerates heart rate, mimicking the effects of chronic cardiac stress. This technique is widely used in cardiovascular research to investigate the genetic and molecular mechanisms of heart disease, study the impact of pharmacological treatments, and identify potential therapeutic targets. Pacing-induced heart failure in Drosophila offers a scalable and efficient model to examine heart function, providing insights that are applicable to human heart disease research.

Leveraging our expertise in Drosophila heart models and pacing technologies, we offer a variety of services that support cardiovascular research, from genetic screening to drug testing. Our services enable researchers to gain valuable insights into heart disease progression and evaluate the effects of potential therapies in a high-throughput, cost-effective model system.

What We Offer

• Pacing-Induced Heart Failure Model

Establishment of pacing-induced heart failure models in Drosophila, enabling the study of cardiac stress, heart disease mechanisms, and therapeutic interventions.

• Cardiac Function Monitoring Service

Real-time monitoring of heart function and rhythm in Drosophila using advanced imaging and pacing techniques to evaluate the impact of genetic and pharmacological interventions.

• Genetic Screening for Heart Disease Genes

High-throughput genetic screening in Drosophila to identify genes involved in heart failure and cardiomyopathy, ideal for discovering novel therapeutic targets.

• Drug Efficacy Testing for Cardiovascular Therapies

Testing of pharmacological compounds in Drosophila heart failure models to assess their efficacy in mitigating heart failure and improving cardiac function.

Why Choose Us

• High-Precision Pacing Technology

Our advanced pacing systems provide precise control over heart stimulation, ensuring accurate and reproducible heart failure models in Drosophila.

• Comprehensive Cardiac Monitoring

We offer real-time imaging and monitoring of heart function, enabling detailed analysis of heart failure progression and therapeutic effects.

• Cost-Effective Cardiovascular Research

Drosophila models provide an economical alternative to mammalian models for early-stage cardiovascular research, allowing for high-throughput screening.

• Expertise in Heart Disease Models

Our team has extensive experience in developing and utilizing Drosophila heart models, ensuring reliable data and successful study outcomes.

Our Resources

Pacing System (IonOptix MyoPacer)

The IonOptix MyoPacer system allows for precise electrical stimulation of Drosophila hearts, enabling controlled pacing for heart failure induction and monitoring of heart rate and rhythm.

High-Resolution Imaging System (Zeiss LSM 980)

This confocal imaging system provides high-resolution imaging of Drosophila heart structure and function, allowing for detailed analysis of cardiac abnormalities and disease progression.

Automated Behavioral Monitoring System (Noldus EthoVision XT)

Our EthoVision XT system tracks the locomotor and behavioral effects of heart disease in Drosophila, offering insights into the systemic impact of heart failure.

STEMart provides high-quality animal model services tailored to meet the specific needs of our clients. Our team of experienced specialists utilizes cutting-edge equipment and adheres to rigorous quality control protocols, ensuring precise and dependable results. Contact us to learn more about our animal model services and how we can help you achieve your research goals.