Drug Metabolism Service Based on LC-MS/MS

STEMart offers specialized Drug Metabolism Services using advanced LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry), a powerful tool for analyzing the metabolic pathways of pharmaceutical compounds. In our laboratory, LC-MS/MS plays a crucial role in providing precise and detailed data on drug metabolism, enabling us to quantify metabolites and identify metabolic pathways with exceptional sensitivity and accuracy. This technology is essential for drug development, pharmacokinetic studies, and safety assessments, offering reliable data to support your research and regulatory submissions.

LC-MS/MS combines the separation capabilities of liquid chromatography with the high sensitivity and specificity of tandem mass spectrometry. The technology operates by first separating drug metabolites in a liquid chromatography system, followed by mass analysis in a tandem mass spectrometer, where precursor ions are selected, fragmented, and analyzed to provide detailed structural information. LC-MS/MS is widely used in the pharmaceutical industry for studying drug metabolism, identifying potential drug-drug interactions, and evaluating the pharmacokinetics of new compounds.

Leveraging our expertise in mass spectrometry and the advanced capabilities of LC-MS/MS, STEMart offers a comprehensive range of drug metabolism services tailored to meet the specific needs of our clients. From metabolite identification to pharmacokinetic profiling, our services provide high-quality data and insights to advance your drug development projects.

What We Offer

• Metabolite Identification

We provide precise identification of drug metabolites using LC-MS/MS, offering detailed insights into the metabolic pathways of pharmaceutical compounds.

• Pharmacokinetic Profiling

Our service includes the analysis of drug absorption, distribution, metabolism, and excretion (ADME) using LC-MS/MS, providing essential data for drug development and safety assessments.

• Metabolic Stability Testing

We assess the stability of drug compounds in various biological matrices, helping to predict the in vivo behavior of drugs and identify potential liabilities.

• Drug-Drug Interaction Studies

Using LC-MS/MS, we investigate potential drug-drug interactions by analyzing the effect of co-administered drugs on the metabolism of the test compound.

Why Choose Us

• High Sensitivity and Specificity

Our LC-MS/MS technology provides high sensitivity and specificity, ensuring accurate detection and quantification of metabolites in complex biological samples.

• Comprehensive Metabolic Analysis

We offer extensive coverage of metabolic pathways, providing a complete understanding of drug metabolism and potential interactions.

• Regulatory Expertise

Our team is experienced in generating data that meets regulatory standards, supporting your submissions with reliable and compliant data.

Our Equipment

LC-MS/MS

This advanced system combines liquid chromatography with tandem mass spectrometry, offering precise separation and analysis of drug metabolites in complex biological matrices.

Nano-LC-MS/MS

Enhancing our drug metabolism capabilities, this system provides nano-scale separation and detailed analysis of metabolites, offering superior sensitivity for pharmacokinetic studies.

Triple Quadrupole MS

Complementing our LC-MS/MS system, this instrument delivers targeted quantification of specific metabolites, ensuring accurate and reproducible results for drug metabolism studies.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.