Epidermal GF (EGF) detection service (CAT#: STEM-MB-0252-WXH)

Introduction

Epidermal growth factor (EGF) is an important cell growth factor secreted by the human body. It is abundant in human epithelial cells. Its functions include stimulating the growth of epithelial cells and endothelial cells, promoting the proliferation of epithelial cells and fibroblasts. In addition to regulating cell proliferation and differentiation, EGF, as a lung regulatory peptide, has anti-oxidant effects, and can regulate the function of airway epithelial cells through autocrine or paracrine methods. EGF can up-regulate the expression of γ-glutamyl transpeptidase, accelerate the transport of exogenous glutathione (GSH) into cells, promote the synthesis of GSH, improve the antioxidant capacity of cells, and eliminate reactive oxygen species. In addition, EGF has a significant regulatory effect on alveolar cell proliferation, and thus participates in the lung injury repair process. Moreover, EGF also has a certain regulatory effect on the reproductive system. EGF affects testicular development and spermatogenesis, regulates ovarian development, and promotes zygotic development. It can also be used as an embryonic nutrient factor to regulate early embryo development.