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FiltraLinX Benchtop TFF System, Membrane Filters: 0.1-0.5 m² (CAT#: STEM-GLE-0038-ZJF)

Highlights

Hollow fiber filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or scale-down;
Various specifications available: 0.017-1.1 m2 hollow fiber filters;
Equipped with the electric proportional control valve, pressure sensor, etc., realizing automatic adjustment of TMP;

Cat Number: STEM-GLE-0038-ZJF

Application: Automatic control of TMP and Delta P, thereby realizing automated operations such as concentration, diafiltration, desalting and dealcoholization of bioproducts

Model: Membrane Filters: 0.1-0.5 m²

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Description

The FiltraLinX® benchtop TFF system features a modular design, equipped with membrane filter holders of various specifications to meet filtration area requirements of 0.1-0.5 m² or 0.5-2.5 m². Depending on process requirements, the circulating pump can be configured with either a rotor pump or a diaphragm pump.
Designed to be compact and practical, the system includes an automatic control system for flow rate and pressure, enabling automatic control of TMP and Delta P. This allows for automated operations such as concentration, diafiltration, desalting, and dealcoholization of bioproducts like antibodies, vaccines, blood products, and gene therapy drugs.
With features like automated operation, cost-effectiveness, and compliance with data integrity regulations, the system is an ideal choice for laboratory research, pilot-scale production, clinical drug production, and Good Manufacturing Practice regulations production stages.

Specification

In-process tank: 5 L
Equipment dimensions and weight: 950 × 560 × 1450 mm and 130 kg
Automatic control level: Automatic control
Operating pressure: Max. 5 bar
System pressure resistance: Max. 6 bar
Pipeline fittings: SS 316L; Ra ≤ 0.4 μm
Sanitary connection: TC chuck
Manual valve: PP, SS 316L
Flow detection: Permeate end, electromagnetic flow meter; retentate end; electromagnetic flow meter
Operation mode: Automatic feedback control
Operating temperature: 4 – 40 °C @ PP; 4-60 °C @ SS 316L
Min. circulation volume: 0.1-0.5 m² benchtop model: minimum circulation volume ~ 200 mL
Language: Chinese, English
Material (liquid contact part): Common and classic materials in the pharmaceutical industry such as 316 L, Polymer (USP class VI or Food and Drug Administration), EPDM, Santoprene elastomer, medical, Grade epoxy, silicone

Features

Hollow fiber filtration family with consistency and linearity, which can ensure the seamless transition of process scale-up or scale-down;
Various specifications available: 0.017-1.1 m2 hollow fiber filters;
Equipped with the electric proportional control valve, pressure sensor, etc., realizing automatic adjustment of TMP;
Fully functional with data recording, audit trial, permission management, etc.;
Flexible connections, compatible with single-use storage and mixing bags used for the collection of product concentrations;
Equipped with filtration tank, used for the temporary storage of the product concentration, defiltration, harvests and clarifications;
Capable of automatically performing both the water flux test and the filter test;
With high compatibility, compatible with hollow fiber filters and cassettes membrane;
The frame is made of wear-resistant 304 stainless steel, and the part in contact with the product is made of 316L stainless steel;
Polishing for the outer surface Ra ≤ 1.2 μm, polishing for the part in contact with the product Ra ≤ 0.4 μm;
The part in direct contact with the feed liquid is made of sanitary grade materials, such as 316L stainless steel, EPDM/PTFE/ TPE, etc. Certifications of the materials are available upon request;
System pipeline withstands pressure up to 6 bar;
Full set of accessories including hollow fiber bracket, allowing for use upon arrival directly.

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