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Gene Knockdown Service Based on RNAi Technology in Drosophila

STEMart offers a specialized Gene Knockdown Service utilizing RNA interference (RNAi) technology in Drosophila (fruit fly) models to silence specific gene expression with high precision. RNAi is a powerful technique that allows for targeted gene knockdown, enabling researchers to study gene function and regulation in a well-established model organism. Our laboratory is equipped with state-of-the-art RNAi delivery systems and advanced screening platforms, allowing us to effectively knock down genes of interest and study their roles in various biological processes.

RNAi technology works by introducing double-stranded RNA (dsRNA) molecules into Drosophila, which triggers the degradation of the corresponding mRNA, effectively reducing the expression of the targeted gene. This method is widely applied in genetics, developmental biology, neurobiology, and disease modeling, offering a robust and scalable approach to investigate gene function. By silencing specific genes, researchers can uncover gene roles in pathways, identify potential therapeutic targets, and explore genetic interactions in a highly controlled environment.

Leveraging our expertise in Drosophila genetics and RNAi technology, we offer a comprehensive range of gene knockdown services tailored to your research needs. Whether you are investigating gene function, studying disease models, or conducting large-scale genetic screens, our services provide accurate and reproducible results to advance your research goals.

What We Offer

  • Targeted Gene Knockdown Service

Silencing of specific genes in Drosophila using RNAi technology to study gene function and its effects on biological processes.

  • Tissue-Specific Knockdown Service

Inducible, tissue-specific gene knockdown to explore gene function in specific tissues or developmental stages, using the GAL4-UAS system in Drosophila.

  • Functional Genomics Screening

Large-scale RNAi screening for functional genomics studies, allowing researchers to identify key genes involved in specific biological pathways or diseases.

  • Developmental and Behavioral Studies

RNAi-mediated knockdown in Drosophila to investigate the impact of gene silencing on development, behavior, and phenotype.

Why Choose Us

  • Precision Gene Silencing

Our RNAi technology offers precise, targeted gene knockdown, ensuring high specificity and minimal off-target effects in Drosophila models.

  • Customized Solutions

We provide flexible study designs tailored to your research, whether you need tissue-specific knockdown or large-scale genetic screening.

  • Experienced Team

Our team has extensive expertise in Drosophila genetics and RNAi technology, providing reliable support throughout your research project.

  • Scalable Screening Capabilities

Our advanced RNAi screening platforms allow for high-throughput gene knockdown, enabling large-scale functional studies with rapid turnaround.

Our Resources

RNAi Delivery System (FlyBase RNAi Library)

We utilize the comprehensive FlyBase RNAi library, which contains RNAi lines targeting thousands of genes in Drosophila, providing extensive coverage for gene knockdown studies.

Confocal Imaging System (Zeiss LSM 980)

Our Zeiss LSM 980 confocal microscope provides high-resolution imaging for analyzing the phenotypic effects of gene knockdown in Drosophila tissues and cells.

Drosophila Breeding and Screening Platform (TriKinetics Drosophila Activity Monitor)

This system allows for automated tracking and analysis of Drosophila behavior and activity post-RNAi treatment, facilitating behavioral studies and developmental analysis.

STEMart provides high-quality animal model services tailored to meet the specific needs of our clients. Our team of experienced specialists utilizes cutting-edge equipment and adheres to rigorous quality control protocols, ensuring precise and dependable results. Contact us to learn more about our animal model services and how we can help you achieve your research goals.

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