Genetic Mutation Service Based on CRISPR-Cas9 Technology

STEMart offers an innovative Genetic Mutation Service using CRISPR-Cas9 technology to precisely modify genes in various organisms. This powerful gene-editing technique allows for targeted mutations, knockouts, or gene insertions, providing a flexible and efficient solution for genetic research. Our laboratory uses advanced CRISPR-Cas9 tools to achieve highly specific modifications, supporting projects in fields such as developmental biology, genetics, and disease modeling.

CRISPR-Cas9 works by using a guide RNA to target specific DNA sequences, while the Cas9 enzyme creates double-strand breaks at these locations. This enables the introduction of mutations or the removal of specific genes. Widely used in genomics, biomedical research, and therapeutic development, CRISPR-Cas9 has transformed genetic studies by offering unprecedented precision and efficiency in editing the genome. Our service is ideal for creating genetic models, studying gene function, and developing therapeutic strategies.

Leveraging our expertise in CRISPR-Cas9 technology, we provide a comprehensive suite of services, including gene knockout, point mutation creation, and gene editing in a variety of organisms. Our tailored approach ensures that your project’s specific needs are met with accuracy and reliability, helping researchers make significant advancements in genetic and biomedical studies.

What We Offer

• Gene Knockout Service

Generation of precise gene knockouts in various organisms using CRISPR-Cas9, allowing researchers to study the impact of specific gene deletions on biological functions.

• Point Mutation Creation Service

Introduction of targeted point mutations to modify specific nucleotides in the genome, facilitating the study of genetic variations and their effects on phenotype.

• Gene Insertion Service

Insertion of specific genes or genetic elements into the genome using CRISPR-Cas9, enabling the exploration of gene function and the creation of transgenic models.

• Conditional Knockout Service

Using CRISPR-Cas9 with conditional systems (e.g., Cre-LoxP), we create tissue-specific or time-specific knockouts for studying gene function under controlled conditions.

• Gene Editing in Zebrafish, Mice, and Other Models

CRISPR-Cas9-mediated gene editing in a variety of model organisms, allowing researchers to use relevant genetic models for their research.

Why Choose Us

• Precision Gene Editing

Our CRISPR-Cas9 service ensures precise gene targeting with minimal off-target effects, offering reliable and reproducible results for your genetic studies.

• Comprehensive Service Range

From design to validation, we provide full support throughout your CRISPR-Cas9 project, ensuring all aspects of gene editing are covered.

• Experienced Team of Genetic Engineers

Our team of experts has extensive experience in gene editing and provides customized solutions tailored to meet the unique demands of your research.

• Versatile Editing Options

We offer a wide range of gene editing services, including knockouts, insertions, and mutations, allowing flexibility in study design and application.

Our Resources

CRISPR-Cas9 Gene Editing Platform

Our CRISPR-Cas9 platform, powered by Thermo Fisher Scientific, provides high efficiency and accuracy in gene editing, enabling precise genetic modifications.

Microinjection System (Eppendorf FemtoJet 4i)

This system ensures accurate delivery of CRISPR components into cells or embryos, facilitating efficient gene editing in model organisms.

Next-Generation Sequencing System (Illumina NovaSeq 6000)

The Illumina NovaSeq 6000 allows for comprehensive sequencing of edited genomes, providing in-depth analysis and validation of CRISPR-induced mutations.

STEMart provides high-quality animal model services tailored to meet the specific needs of our clients. Our team of experienced specialists utilizes cutting-edge equipment and adheres to rigorous quality control protocols, ensuring precise and dependable results. Contact us to learn more about our animal model services and how we can help you achieve your research goals.