Heparin Affinity Resins, UniGel-65Heparin 10mL (CAT#: STEM-C-3764-ZJF)

Heparin, a linear and highly sulfated glycosaminoglycan, is known for its anti-coagulant properties. Its polyanionic nature allows it to interact with a diverse range of biomolecules, including plasma coagulation proteins, lipoprotein lipase, collagenase, and DNA polymerase. Immobilized heparin is commonly utilized as an affinity chromatography adsorbent for purifying biological substances.
Two heparin affinity resins are available with different matrices to cater to varied applications. UniGel-65Heparin, featuring a monodisperse polymethacrylate matrix, offers excellent mechanical strength, making it ideal for fast-flow operations. Its robust performance makes it suitable for both bioprocessing and sample preparation applications.
NM90Agarose Heparin, based on crosslinked agarose, provides competitive binding capacity. This resin serves as an effective alternative when high flow rates are not required in the chromatography process.

Chromatography Technique: Heparin affinity
Matrix: Polymethacrylate
Particle Size: 65 μm
Ligand: Heparin
Dynamic Binding Capacity: ~5 mg·mL⁻¹ (ATIII)
Maximum Pressure: 0.8 MPa
Clean In Place: 2 M NaCl
Recommended Flow Velocity: 100-500 cm/h
pH Stability: 4-10
Chemical Stability: Stable in commonly aqueous used buffers, 0.1 M NaOH, 0.05 M NaAc, 8 M urea, 6 M guanidine hydrochloride, non-ionic detergent, 10% glycerin, etc.
Operational Temperature: 2-40 ℃
Storage: 20% Ethanol, 4-25 ℃

Anti-Coagulant Properties: Heparin is a highly sulfated glycosaminoglycan with anti-coagulant effects, useful in affinity chromatography.
UniGel-65Heparin: Monodisperse polymethacrylate matrix offering superior mechanical strength for fast flow operations and robust performance.
High Flow Rate Capability: UniGel-65Heparin is ideal for bioprocessing heparin affinity chromatography and sample preparation.
NM90 Agarose Heparin: Based on crosslinked agarose, providing competitive binding capacity, suitable for applications where high flow rate is not necessary.
Versatile Heparin Affinity Resins: Two types available—UniGel-65Heparin for high flow and NM90 Agarose Heparin for alternative processes.

STEM-C-3762-ZJF
STEM-C-3763-ZJF
STEM-C-3765-ZJF
STEM-C-3766-ZJF