Unlock Exclusive Discounts & Flash Sales! Click Here to Join the Deals on Every Wednesday!
Nucleobase-modified aptamers are attractive candidates for diagnostic and therapeutic agents due to the high affinity, stability and functionality. However, since even conventional SELEX requires many selection rounds, acquisition of modified aptamers is much more laborious. In this service, microbeads-assisted capillary electrophoresis (MACE)-SELEX is applied against thrombin using the indole-modified DNA library. This is a promising approach for rapid identification of modified aptamers.