Host-Microbiome Interaction Studies

Host-microbiome interaction studies investigate the complex relationship between the host organism and the microbes that reside in or on it. These studies aim to understand how the microbiome influences the health and development of the host, as well as how the host's immune system interacts with the microbiome.

What We Can Do for You

Microfluidics is a powerful tool for studying host-microbiome interactions due to its numerous advantages that can lead to a better understanding of the complex relationships between hosts and their associated microbiomes.

• Precise control over the conditions of the experiment, such as flow rates, concentrations, and spatial distributions
• High-throughput screening of multiple samples in parallel, allowing quick and efficient analysis of a large number of host-microbiome interactions.
• Reduced sample volumes and lower reagent costs.
• Real-time monitoring of host-microbiome interactions with incorporated sensors and imaging technologies, providing valuable insights into the dynamics of these interactions and allowing the detection of transient or short-lived events.
• Study of localized interactions between hosts and microbiomes provides important information about how these interactions vary across different regions of the host organism.

STEMart integrates multiple techniques with microfluidic device for studying host-microbiome interactions.

• Microfluidic device integrated with fluorescence microscopy: Fluorescently-labeled host cells and microbiome cells can be introduced into the microfluidic device, and their interactions can be observed and tracked in real-time using fluorescent imaging. This allows researchers to visually monitor the behavior of individual cells and study how they interact with each other within the microenvironment of the device.
• Microfluidic device integrated with electrochemical sensors: Measure the levels of specific metabolites or signaling molecules produced during host-microbiome interactions
• Microfluidic device integrated with single-cell analysis: Characterize the gene expression of individual cells, providing insights into the molecular mechanisms underlying host-microbiome interactions.

For more information about our service about host-microbiome interaction studies, please contact us.