Human Recombinant IHH, STEMCELL Technologies (CAT#: STEM-CT-0892-ZJF)

Indian hedgehog (IHH) is one of three proteins in the hedgehog family which includes sonic hedgehog and desert hedgehog. Hedgehog proteins are important signaling molecules, acting through patched and smoothened receptors. During embryonic development, they are expressed in the fetal lung, gut, stomach, liver, kidney, and pancreas. IHH is strongly expressed in cartilage and regions of developing bone, and its signaling regulates growth and differentiation of bone tissue (Marigo et al.; Valentini et al.; St-Jacques et al.). IHH is also involved in yolk sac vasculogenesis, indicating a role in the differentiation of epiblast cells into endothelial and red blood cells (Byrd et al.). IHH induces the expression of parathyroid hormone-related peptide (PTHrP), which negatively regulates IHH during chondrocyte differentiation and proliferation (Vortkamp et al.).

Subtype: Cytokines
Cell Type: Endothelial Cells, Mesenchymal Stem and Progenitor Cells, Red Blood Cells
Species: Human
Area of Interest: Endothelial Cell Biology, Stem Cell Biology
Purity: ≥ 95%

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

Human Recombinant IGF-II, STEMCELL Technologies
Human Recombinant IGFBP-4, STEMCELL Technologies
Human Recombinant IL-1 alpha, STEMCELL Technologies
Human Recombinant IL-1 beta, STEMCELL Technologies