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Human Recombinant NT-4, STEMCELL Technologies (CAT#: STEM-CT-0933-ZJF)

Highlights

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

Cat Number: STEM-CT-0933-ZJF

Application: Neurotrophin 4, for cell activation, expansion, or differentiation

Model: 78093

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Description

Neurotrophin-4 (NT-4) is a member of the nerve growth factor family which includes neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and nerve growth factor (NGF), all of which promote the differentiation, growth, and survival of peripheral and central nervous system neurons (Eide et al.). NT-4 binds and activates tropomyosin receptor kinase B (TrkB) at the cell surface; in doing so, it acts as a survival factor for certain populations of sensory neurons (Berkemeier et al.; Skaper). It has been shown that NT-4, together with BDNF, promotes neurite extension and maturation, as well as maintenance of differentiated cerebellar granule cells (Gao et al.).

Specification

Subtype: Cytokines
Cell Type: Astrocytes, Neural Cells, PSC-Derived, Neural Stem and Progenitor Cells, Neurons
Species: Human
Area of Interest: Neuroscience, Stem Cell Biology
Purity: ≥ 95%

Features

Reliable Consistency: Guarantees uniformity and repeatability in various applications with endotoxin levels below 0.2 EU/μg.
Free of Animal Components: Completely devoid of any animal or human-derived elements.
Broad Selection: Offers a wide range of human, mouse, and rat cytokines available in multiple sizes.

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