Hypothyroidism Animal Model (CAT#: STEM-AE-0078-WXH)

• Primary hypothyroidism and thyroid hormone (TH) resistance syndrome research.
• Research on the action of thyroid hormones, drug pharmacology, etc.

• Antithyroid drug-induced hypothyroidism model: Drugs include methylthiouracil (MTU) and propylthiouracil (PTU). Drugs were introduced into rats by intraperitoneal injection, gavage, or dissolved in drinking water.
• Congenital hypothyroidism model: removal of the thyroid gland during the embryonic period or administration of antithyroid drugs can reduce the synthesis or (and) release of thyroxine in animals, resulting in hypothyroidism, resulting in congenital disorders mainly of central nervous system developmental retardation.