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In Vivo Pharmacodynamic Evaluation of Atopic Dermatitis Mouse Disease Model (CAT#: STEM-AE-0678-LGZ)

Introduction

Atopic dermatitis (AD) is a chronic skin disorder characterized by itchiness, rashes, and squamous lesions associated with cardiovascular, psychiatric disorders (depression, anxiety, sleep disorders, etc.) and other diseases. In order to better study specific dermatitis, researchers have developed a variety of animal models of specific dermatitis in mice, including (1) AD model caused by enhanced skin sensitization using epithelial sensitive antigens and haptens; (2) AD model of genetically engineered mice; (3) Spontaneous AD mouse model.




Principle

Experimental animal: C57BL/ 6,7 weeks old, female
Molding reagent: OXA (oxazolone)
Modeling method:
Sensitization - Day0 smear right ear + back
Inspire - Day7~Day25 smear right ear + back

Applications

Autoimmune Disease

Procedure

1. Disease model construction.
2. Mice dosing.
3. Efficacy monitoring.
4. Biochemical detection of tissue samples.

Materials

• Sample Type: liquid or powder
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