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The mouse Epcam gene was replaced by human EPCAM coding sequence in B-hEPCAM EL4 cells. Human EPCAM is highly expressed on the surface of B-hEPCAM EL4 cells.
B-hEPCAM EL4 cells have the capability to establish tumors in vivo and can be used for efficacy studies.
Common name: B-hEPCAM EL4
Aliases: DIAR5, EGP-2, EGP40, ESA, HNPCC8, TROP1
Organism: Mouse
Tissue types: Lymphoma
Disease: Lymphoma
Strain: C57BL/6N
Tissue: T lymphocyte