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In Vivo Pharmacodynamic Evaluation of Spontaneous Diabetes Model (B-ob/ob Mice) (CAT#: STEM-AE-0662-LGZ)

Introduction

Metabolic diseases are diseases caused by the accumulation or deficiency of certain metabolic substances such as sugars, fats, proteins (amino acids), purines, pyrimidines, and copper when biochemical processes in the body are disrupted. Symptoms vary in severity and diagnosis depends on clinical manifestations and blood, urine and other biochemical tests. There is no effective cure, the main is to eliminate the cause and symptomatic treatment. The prognosis depends on the etiology, severity of symptoms and treatment effect.




Principle

Diabetes is an important disease that threatens human health at present. The ob/ob mouse is currently one of the best animal models for the study of human type 2 diabetes. The biological characteristics and physiological and biochemical indicators of model mice are common and important reference indicators in various experiments.

Applications

Metabolic Disease

Procedure

1. Disease model construction.
2. Mice dosing.
3. Efficacy monitoring.
4. Biochemical detection of tissue samples.

Materials

• Sample Type: liquid or powder
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