Inborn Errors of Metabolism Screening Service Based on Tandem MS

STEMart offers advanced screening services for Inborn Errors of Metabolism (IEM) using Tandem Mass Spectrometry (Tandem MS), a powerful tool for detecting metabolic disorders at an early stage. In our laboratory, Tandem MS plays a crucial role in identifying abnormal metabolic patterns by precisely measuring amino acids, organic acids, and other metabolites in newborns and children. This technology is essential for early diagnosis, treatment, and management of metabolic diseases, ensuring timely intervention and improved patient outcomes.

Tandem MS works by first ionizing metabolites in biological samples and then separating them based on their mass-to-charge ratios in two stages of mass spectrometry. This allows for the simultaneous detection of multiple metabolites with high sensitivity and specificity. Widely used in clinical screening, Tandem MS is the gold standard for diagnosing a wide range of metabolic disorders, including aminoacidopathies, organic acidurias, and fatty acid oxidation disorders.

Leveraging our expertise in metabolic screening and the advanced capabilities of Tandem MS, STEMart offers a comprehensive range of Inborn Errors of Metabolism screening services. Our services provide the critical data needed for early detection, diagnosis, and treatment planning, supporting healthcare providers and families in managing these complex disorders.

What We Offer

• Comprehensive IEM Screening

We provide broad-spectrum screening for a wide range of metabolic disorders, detecting abnormalities in amino acids, organic acids, and acylcarnitines with high accuracy.

• Targeted Metabolite Analysis

Our service includes targeted analysis of specific metabolites to confirm suspected metabolic disorders, offering detailed insights into the patient’s metabolic profile.

• Newborn Screening

Using Tandem MS, we offer newborn screening services to detect inborn errors of metabolism at an early stage, supporting timely treatment and improved patient outcomes.

Why Choose Us

• High Sensitivity and Precision

Our Tandem MS system provides exceptional sensitivity and precision, ensuring accurate detection of metabolic abnormalities even at low concentrations.

• Comprehensive Coverage

We offer extensive coverage of metabolic disorders, providing healthcare providers with a complete picture of potential inborn errors of metabolism in their patients.

• Rapid Turnaround

Our efficient screening process ensures rapid turnaround times, allowing for timely diagnosis and intervention, which is critical for managing metabolic disorders.

Our Equipment

Tandem MS (MS/MS)

This system combines two stages of mass spectrometry, enabling the precise detection and quantification of multiple metabolites in a single run, ideal for screening inborn errors of metabolism.

Triple Quadrupole MS

Enhancing our Tandem MS capabilities, this instrument provides high sensitivity and specificity for targeted metabolite analysis, supporting accurate diagnosis of metabolic disorders.

LC-MS/MS

This system is used for detailed metabolite analysis, providing high-resolution separation and detection, which is essential for comprehensive IEM screening.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.