Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry (CAT#: STEM-ST-0100-LJX)

Introduction

Recent advances in mass spectrometry approaches to the analysis of lipids include the ability to incorporate both lipid class identification with lipid structural information for increased characterization capabilities. The detailed examination of lipids and their biosynthetic and biochemical pathways made possible by novel instrumental and bioinformatics approaches is advancing research in fundamental cellular and medical studies. Recently, high-throughput structural analysis has been demonstrated through the use of rapid gas-phase separation on the basis of the ion mobility (IM) analytical technique combined with mass spectrometry (IM-MS). IM-MS has been extensively utilized in biochemical research for peptide, protein and small molecule analysis.