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It is well known that the negative effects on human health besides climate implica-tions, within the context of the phenomenon of atmospheric pollution, of fine dusts (PM 10, PM 2.5) constitute a priority. However, for the purposes of a proper action of preservation and of prevention with regard to exposed cultural property and the interaction of the aforesaid dusts with these artefacts, it is opportune to note how such action of alteration/degradation could also occur within confined spaces, such as museums, libraries and archives. Particularly, the presence of a high quantity of dusts within the area where frescoes, paintings, sculptures and works of art in general are situated, should be readily surveyed to allow the prevention of any dangerous situation.