Measurement of Serum Viscosity by Capillary Viscometer (CAT#: STEM-PPA-0004-YJL)

Introduction

Plasma and serum viscosity measurements have an important role in the clinical management of patients prone to hyperviscosity syndrome. Hyperviscosity syndrome can occur in association with a variety of clinical diagnoses, such as polycythemia, Waldenström macroglobulinemia, multiple myeloma, and leukemia. The viscosity at which symptoms develop is variable, but they rarely appear below a serum or plasma viscosity of 3 cP. Therefore, accurate measurement of serum or plasma viscosity is an important component of patient management.

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Principle Applications Procedure Materials Notes Related Products

Principle

A capillary viscometer is an instrument used to measure the viscosity, or thickness, of a liquid by measuring how long it takes the liquid to flow through a small-diameter tube, or capillary. The flow, or efflux, time is directly proportional to the liquid's kinematic viscosity, and may be converted directly to viscosity by use of a conversion factor unique to each instrument. Viscosity is generally temperature dependent, so the capillary viscometer is usually used in a controlled-temperature water bath set to a specific temperature.
The capillary method is used to determine the viscosity of a Newtonian fluid (a liquid with a viscosity independent of the shearing stress or rate of shear). Capillary viscometer calculations are performed using suspended level capillary viscometers and Ostwald-type capillary viscometers.

Applications

Mineral oil industry; Food industry; Cosmetic/pharmaceutical industry; Petroleum industry

Procedure

1. Select the capillary viscometer and load the sample.
2. Adjust the bath temperature.
3. Determine the efflux time of the sample.

Materials

• Sample Type: Newtonian fluid

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