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Multicolor FISH (mFISH) is a method to facilitate analysis of each single chromosome or chromosome part of a metaphase. Thus, marker chromosomes, complex chromosomal rearrangements, and all numerical aberrations can be visualized simultaneously in a single hybridization experiment. Advantages of M-FISH include rapid analysis of metaphase spreads, even in complex cases with multiple chromosomal rearrangements, and identification of marker chromosomes.
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