OK432, Seafrom (CAT#: STEM-CT-0048-ZJF)

The OK432 manufactured by Seafrom is suitable for its immunostimulant properties in experimental studies.
OK432 is a lyophilized vaccine that activates neutrophils, enabling them to kill cancer cells treated with IFN-γ or TNF-α. The cytotoxicity of neutrophils induced by OK432 against autologous tumor cells is mediated through the interaction between CD11b/CD18 and ICAM-1. Monocytes induced by OK432 can also eliminate autologous tumor cells. Stimulation of lymphocytes by OK432 results in the display of LAK (lymphokine-activated killer) cell activity, and these activated lymphocytes even exhibit activity against tumor cells resistant to NK (natural killer) cells.
The lyophilized formulation can be stored at 2-8°C for 24 months. For reconstitution, it can be diluted with sterile water, saline, culture medium, or PBS, with a final concentration not lower than 100μg/mL. Avoid repeated freeze-thaw cycles.

Activity: NK cells activated by this product exhibit a cytotoxic index (T-C) not less than 15%
Appearance: White loose body

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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