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Osteoarthritis Animal Model (CAT#: STEM-AE-0021-WXH)

Introduction

Degenerative osteoarthritis, also known as osteoarthritis, degenerative arthritis, senile arthritis, hypertrophic arthritis, is a degenerative disease. It is caused by many factors such as aging, obesity, strain, trauma, congenital abnormalities of joints, joint deformities and other factors, such as articular cartilage degeneration injury, joint edge and subchondral bone reactive hyperplasia. This disease is more common in middle-aged and elderly people, and it is more likely to occur in weight-bearing joints and joints with more activities.




Applications

• Study the pathogenesis and treatment of osteoarthritis.
• Drug development, drug screening and efficacy research.

Procedure

• Method 1. Anterior cruciate ligament transection (ACLT).
• Method 2. Lateral collateral ligament and meniscus transection (MNX).
• Method 3. DMM (Meniscal Destabilization) Modeling Induces Osteoarthritis in Mice.
• Method 4. Collagenase Induction of Osteoarthritis.

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