Osteogenesis Differentiation of MSC (CAT#: STEM-CBT-0038-WXH)

Introduction

MSCs are a population of stromal cells present in the bone marrow and most connective tissues, capable of differentiating into mesenchymal tissues such as bone and cartilage. MSCs from different sources are not necessarily equivalent. Indeed, they have shown significant functional differences and most certainly require specific optimal culture conditions and differentiation protocols for osteogenesis differentiation. MSCs can be used for differentiation into osteogenic lineages to form bone. The process involves three distinct stages from the commitment of osteoprogenitor cells, pre-osteoblasts differentiation, and mature osteoblasts formation.