Pall iCELLis Nano Single-Use Fixed Bed Bioreactor w/ mPath Controller, Pall Corporation (CAT#: STEM-CCPO-0020-ZJF)

The Pall iCELLis Nano Single-Use Fixed Bed Bioreactor w/ mPath Controller is manufactured by Pall Corporation.
The iCELLis bioreactor system is an automated, single-use, fixed-bed bioreactor, that provides excellent cell growth conditions for adherent cells.
Central to the iCELLis bioreactor technology is the use of a compact fixed-bed, filled with proprietary microcarriers. This matrix is made of class VI(1) polyester microfibers and provides a surface area for cell growth up to 500 m2. This is the surface equivalent of 3,000 roller bottles (Figure 1). The iCELLis bioreactor comes pre-packed with microcarriers. Because of the cell-to-cell interactions within the 3D environment of the fixed-bed, iCELLis bioreactors can be inoculated at very low density, 3,000 cells per cm2 and even lower points. The seed train can as such be streamlined and simplified, leading to less manual operations and a reduction of associated costs.
Evenly-distributed media circulation is achieved by a built-in magnetic drive impeller, ensuring low shear stress and high cell viability (Figure 2). The cell culture medium flows through the fixed-bed from the bottom to the top. At the top, the medium falls as a thin film down the outer wall where it takes up O2 to maintain high kLa in the bioreactor. This unique waterfall oxygenation, together with a gentle agitation and biomass immobilization, enables the compact iCELLis bioreactor system to achieve and maintain high cell densities - equaling the productivity of much larger stirred-tank units.
The pre-owned products will be thoroughly cleaned and fully tested to perform at manufacturer specifications before shipping.

Condition: Certified Pre-Owned
Electrical: 24V, 7 Amps
Includes:
Pall mPath Control Tower (100-240V, 50/60Hz, 360W, 4 Amps)
(8) iCELLis Single Use Reactor Vessels, Probes, Sensors, and other parts and accessories

Cell culture process simplification, from vial to product
Fully-integrated, single-use iCELLis 500+ bioreactor with disposable, pre-installed calibrated probes
Unique waterfall system for optimal oxygenation and CO2 stripping
Compact high-cell-density, fixed-bed bioreactor providing a significant increase in volumetric productivity vs. traditional stirred tanks
Predictable scalability from R&D to manufacturing
Significant decrease in operational costs and capital investments vs. classical 2D flatware

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