Pharmacokinetic Analysis Service Based on Triple Quadrupole MS

STEMart offers advanced Pharmacokinetic Analysis Services using Triple Quadrupole MS (Mass Spectrometry), a state-of-the-art instrument that provides highly sensitive and precise quantification of drug concentrations in biological samples. In our laboratory, Triple Quadrupole MS is integral to accurately analyzing pharmacokinetics (PK), enabling us to determine the absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds. This technology is essential for drug development, ensuring that compounds meet safety and efficacy requirements before advancing to clinical trials.

Triple Quadrupole MS operates through Multiple Reaction Monitoring (MRM), where selected precursor ions are fragmented, and specific product ions are monitored. This targeted approach allows for the highly selective and sensitive detection of drug compounds and their metabolites, even in complex biological matrices such as plasma, urine, and tissues. Triple Quadrupole MS is widely used in pharmacokinetics to support drug discovery, optimize dosing regimens, and evaluate drug-drug interactions.

Leveraging our expertise in mass spectrometry and the precise capabilities of Triple Quadrupole MS, STEMart offers a comprehensive range of pharmacokinetic analysis services. From determining drug bioavailability to assessing metabolic stability, our services provide the critical data needed to advance your drug development projects.

What We Offer

• Bioavailability and Bioequivalence Studies

We provide detailed analysis of drug absorption and bioavailability, supporting bioequivalence studies that are crucial for generic drug development and regulatory submissions.

• Pharmacokinetic Profiling

Our service includes the complete PK profiling of drugs, analyzing parameters such as Cmax, Tmax, half-life, and clearance to guide drug development decisions.

• Dose-Response Relationship Analysis

We offer analysis of dose-response relationships, helping to optimize dosing regimens and ensure the therapeutic efficacy of drug candidates.

• Drug-Drug Interaction Studies

Our Triple Quadrupole MS technology enables the investigation of drug-drug interactions, identifying potential risks and informing safe combination therapies.

Why Choose Us

• High Sensitivity and Precision

Our Triple Quadrupole MS system offers unmatched sensitivity and precision, ensuring accurate quantification of drugs and metabolites in complex biological samples.

• Comprehensive PK Analysis

We provide thorough pharmacokinetic analysis, offering detailed insights into the ADME properties of drug candidates to support informed decision-making.

• Regulatory Compliance

Our PK analysis services are conducted in accordance with regulatory guidelines, ensuring that your data meets the stringent requirements for drug approval.

• Expert Consultation

Our experienced team provides expert consultation and data interpretation, helping you navigate the complexities of pharmacokinetic studies with confidence.

Our Equipment

Triple Quadrupole MS

This advanced mass spectrometry system is designed for targeted quantification of drugs and metabolites, offering high sensitivity and specificity essential for accurate pharmacokinetic analysis.

LC-MS/MS

Complementing our Triple Quadrupole MS, this system provides precise separation and analysis of drug compounds, enhancing the accuracy of PK profiling.

Nano-LC-MS/MS

This nano-scale liquid chromatography system coupled with tandem mass spectrometry offers superior sensitivity, making it ideal for analyzing low-abundance drug compounds in pharmacokinetic studies.

STEMart provides high-quality mass spectrometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our mass spectrometry services and how we can help you achieve your research goals.