Polymeric RPC Reversed Phase Bulk Media, UniPS® 15-100 (CAT#: STEM-C-3334-ZJF)

Polymeric reverse phase chromatography (RPC) resins serve as valuable alternatives to silica-based RPC media, offering notable advantages such as alkali resistance, extended lifespan, and minimized peak-tailing for basic compounds. These resins are available in a wide range of monodisperse varieties, suitable for applications from submicron UPLC and HPLC packing to medium- and low-pressure FPLC packing. They are widely utilized in laboratory analysis and process-scale purification of diverse chemicals and biomolecules.
The polymeric RPC resin portfolio includes five main types: UniPS, UniPMM, UniPSN, UniPSA, and NM. These provide a broad selection of hydrophobicity and selectivity to meet various purification needs. Among them, the UniPS series is particularly popular in pharmaceutical and biopharmaceutical industries. For example, UniPS 10-300 is commonly used for insulin and peptide purification, UniPS 30-300 is widely applied in oligonucleotide RPC purification, and UniPS 40-300 has proven effective in Vancomycin purification processes.

Matrix: PS/DVB
Particle Size: 3/5/10/15/20/30/40/50 μm
Pore Size: 100/300/500/750/1000/2000/4000 Å
Clean In Place: 80%-100% organic solvent (methanol, ethanol, acetonitrile, isopropanol, etc.) or 0.5M NaOH
Use pH Range: 1-14
Regeneration pH Range: 1-14
Chemical Stability: Stable in commonly used buffers, 1 M HAc, 1 M NaOH, 1 M HCl, 70% ethanol, 30% isopropyl alcohol, 30% acetonitrile, 1% SDS, 6 M guanidine hydrochloride, 8 M urea; avoid long-term exposure to strong oxidants
Operational Temperature: 4-40℃
Storage: 20% Ethanol, 4-25 ℃

Polymeric RPC Resins: Excellent alternatives to silica-based RPC media, offering advantages in alkali resistance, long life, and avoiding peak-tailing of basic compounds.
Wide Range of Applications: Used in UPLC, HPLC, and medium/low pressure FPLC for laboratory analysis and process-scale purification of various chemicals and biomolecules.
Five Product Types: Offers five types of polymeric RPC resins—UniPS, UniPMM, UniPSN, UniPSA, and NM—with varying hydrophobicity and selectivity.
Popular UniPS Series: The UniPS series is widely used in pharmaceutical and biopharmaceutical industries. Examples include UniPS 10-300 for insulin and peptide purification, UniPS 30-300 for oligonucleotide RPC purification, and UniPS 40-300 for efficient Vancomycin purification.

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