Recombinant Human BAFF Protein, Seafrom (CAT#: STEM-CT-0062-ZJF)

The Recombinant Human BAFF Protein manufactured by Seafrom is suitable for B-cell activation and survival in immune responses.
BAFF, or B-Cell Activating Factor, is a member of the Tumor Necrosis Factor (TNF) family. It is expressed in T cells, macrophages, monocytes, and dendritic cells. BAFF is involved in stimulating B-cell and T-cell functions and is a critical factor for peripheral B-cell survival and maturation. BAFF signals through three distinct TNF receptors: TACI, BCMA, and BAFF-R. The human BAFF gene encodes a 285-amino acid type II transmembrane protein, including a 46-amino acid cytoplasmic domain, a 21-amino acid transmembrane domain, and a 218-amino acid extracellular domain.
The lyophilized formulation can be stored at 4°C for 24 months. Once reconstituted, the liquid can be stored at -20°C for 6-12 months, while avoiding repeated freeze-thaw cycles.

Expression Host: HEK293 Cells
Synonyms: BAFF, BLYS, CD257, DTL, TALL-1, TALL1, THANK, TNFSF20, TNFSF13B
Protein Sequence: DNA sequence encodes human BAFF (EAX09101.1) with an Fc tag at the C-terminus, contains 390 amino acids, predicted molecular weight of 44 kD
Purity: ≥95%, analyzed by SDS-PAGE and HPLC
Endotoxin Level: ≤0.01 EU/μg (gel clot method)
Biological Activity: Determined by mouse splenocyte viability assay, expected ED50 effectiveness is 0.5-2.0 g/mL
Purification Method: Chromatographic purification

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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