Recombinant Human BTLA Protein, Seafrom (CAT#: STEM-CT-0119-ZJF)

The Recombinant Human BTLA Protein manufactured by Seafrom is suitable for immune checkpoint regulation.
B and T lymphocyte attenuator (BTLA), also known as B and T lymphocyte-associated protein, and CD antigen CD272, is a protein that contains an Ig-like V-type (immunoglobulin-like) domain. BTLA, or CD272, functions as a lymphocyte inhibitory receptor, suppressing lymphocytes in the immune response process. It interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2 and can also interact with TNFRSF14/HVEM.
Storage Information:
Lyophilized samples can be stored at 4°C for 24 months, and once reconstituted, the liquid can be stored at -20°C for 6-12 months, with care taken to avoid repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: BTLA, CD272
Protein Sequence: The DNA sequence encodes human BTLA Protein (UniProtKB/Swiss-Prot: Q7Z6A9.3), expressed with an Fc tag at the C-terminus.
Molecular Weight: Recombinant human BTLA protein contains 336 amino acids, with a predicted theoretical molecular weight of 40 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity: The concentration of immobilized human HVEM (His tag) is 2 μg/mL (100 μL/well), and it can bind to human BTLA (Fc tag) in a linear range of 0.01-0.3 μg/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

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