Recombinant Human CD160 Protein, Seafrom (CAT#: STEM-CT-0135-ZJF)

The Recombinant Human CD160 Protein manufactured by Seafrom is suitable for immune cell interactions and responses.
The CD160 antigen, also known as Natural Killer Cell Receptor BY55, is a 27 kDa glycoprotein that contains 1 Ig-like V-type (immunoglobulin-like) domain. Its expression is closely associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is found at the cell surface as a tightly disulfide-linked multimer. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 exhibits a broad specificity for binding to both classical and nonclassical MHC class I molecules. When expressed on vascular endothelial cells, CD160 propagates anti-angiogenic signals and promotes apoptosis.
Storage Information:
The lyophilized (freeze-dried) form can be stored at 4°C for 24 months, while the reconstituted liquid can be stored at -20°C for 6-12 months, with a recommendation to avoid repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: CD160, BY55, NK1, NK28
Protein Sequence: The DNA sequence encodes human CD160 (GenBank: AAH14465.1), expressed with a His tag at the C-terminus.
Molecular Weight: Recombinant human CD160 protein contains 133 amino acids, with a predicted theoretical molecular weight of 16.5 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity: Immobilized human HVEM (FC tag) at 5 μg/mL (100 μL/well) can bind to human CD160 (His tag) in a linear range of 2-50 ng/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

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