Recombinant Human CD30 Protein, Seafrom (CAT#: STEM-CT-0133-ZJF)

The Recombinant Human CD30 Protein manufactured by Seafrom is suitable for cell survival and immune responses.
Cluster of Differentiation 30 (CD30), also known as TNFRSF8, is a cell membrane protein belonging to the tumor necrosis factor receptor family and serves as a tumor marker. TNFRSF-8 is expressed on activated, rather than resting, T cells and B cells. Additionally, CD30 is co-expressed with CD15 on classical Hodgkin lymphoma cells. CD30 is the receptor for TNFSF8/CD30L, and it can interact with TRAF2 and TRAF5, mediating signal transduction that activates NF-kappa-B. TNFRSF8 may play a role in regulating cell growth and activating lymphocyte transformation. It is a positive regulator of cell apoptosis and has been shown to limit the proliferative potential of CD8 effector T cells activated by themselves, thereby protecting the body from autoimmune damage.
Storage Information:
The lyophilized (freeze-dried) form can be stored at 4°C for 24 months, while the reconstituted liquid can be stored at -20°C for 6-12 months, with a recommendation to avoid repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: TNFRSF8, CD30, D1S166E, Ki-1
Protein Sequence: The DNA sequence encodes human CD30 (UniProtKB - P28908), expressed with a His tag at the C-terminus.
Molecular Weight: Recombinant human CD30 protein contains 360 amino acids, with a predicted theoretical molecular weight of 40.1 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and high-performance liquid chromatography (HPLC) analysis.
Endotoxin: <0.1 EU/μg
Biological Activity: Immobilized anti-CD30 antibody at a concentration of 1 μg/mL (100 μL/well) can bind to human CD30 (His tag) in a linear range of 2-10 ng/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

Recombinant Human B7-2 Protein, Seafrom
Recombinant Human 2B4 Protein, Seafrom
Recombinant Human CD155 Protein, Seafrom
Recombinant Human CD160 Protein, Seafrom