Separation of α-hydroxy Acids by Immunoaffinity Chromatography (CAT#: STEM-ACM-0060-CJ)

Introduction

α-Hydroxy acids represent one of the most important classes of chiral compounds in nature. Lactic acid, for example, is a key intermediate and end product, respectively, of both prokaryotic and eukaryotic metabolism. In humans, abnormal accumulation of α-hydroxy acids in serum and urine is usually the result of an inherited autosomal recessive disorder causing an enzyme deficiency; however, lactic acidosis, the accumulation of lactic acid in the blood, can also be a potential side-effect of some anti-HIV drugs or be caused by increased bacterial fermentation in the gastrointestinal tract.