Study of the Interactions of Palladium(Ii)-Ceftriaxone Chelate with Anionic Surfactants by Resonance Rayleigh Scattering (CAT#: STEM-ST-0055-YJL)

Introduction

Ceftriaxone (CTRX) is one of the long-efficient and broad-spectrum third generation cephalosporin antibiotics, which is widely used in the clinical at present. It has the strongest activity against gonorrhoeae and chlamydia trachomatis. Clinically, it is often used to treat respiratory tract infection, skin tissue infection, urinary tract infection, osteoarthritis infection and bacteroidal septicemia, and remarkable curative effects have been achieved. It has been used in the front line of treating gonorrhoea. To the study of the pharmacokinetics and recommendation of suitable dosage, it is significant to quantitatively determine the drug both in the pharmaceutical preparations and in body fluids. It is known that in the weak acid medium, Pd(II) can react with CTRX in the presence of sodium lauryl sulfonate (SLS) to form a chelate.