MCAO Animal Model (CAT#: STEM-AE-0042-WXH)

Introduction

The middle cerebral artery occlusion (MCAO) model is an animal model widely used in the study of focal cerebral ischemia. Ischemic cerebrovascular disease (ICVD) is one of the major diseases that threaten human health and survival, and has the characteristics of high morbidity, mortality, disability and recurrence. The middle cerebral artery (MCA) is one of the most common sites of cerebral ischemic injury clinically. The rat MCAO model is usually prepared by intravascular thread occlusion, the principle is to mechanically block the blood supply at the origin of the middle cerebral artery. The characteristics of the MACO model include high reproducibility, precise control of ischemia-reperfusion time, and less invasiveness.