Receptor Occupancy Service Based on Flow Cytometry Systems

STEMart offers specialized Receptor Occupancy (RO) services utilizing cutting-edge flow cytometry systems. Our laboratory utilizes advanced instruments designed for the precise quantification of receptor-ligand interactions at the cellular level. These instruments play a crucial role in our laboratory by enabling high-throughput and highly sensitive analysis, essential for accurate pharmacodynamic studies and therapeutic drug monitoring.

Our flow cytometry systems operate on the principles of fluorescence-based detection, allowing for the measurement of receptor occupancy on a per-cell basis. These systems are equipped with multiple lasers and detectors that enable the simultaneous analysis of multiple parameters, making them indispensable in immunology, oncology, and drug development research. The systems are particularly suited for the detailed study of cell surface receptor dynamics, which is critical for evaluating the efficacy of therapeutic agents.

Leveraging our advanced flow cytometry systems, we offer a comprehensive range of Receptor Occupancy services tailored to meet the specific needs of your research. These services are designed to provide accurate and reliable data, ensuring that your pharmacodynamic studies are supported by robust and reproducible results.

What We Offer

• Quantification of Receptor Occupancy

Precise measurement of receptor occupancy on target cells to assess drug efficacy.

• Pharmacodynamic Studies

Analyze drug-receptor interactions over time to gain insights into drug action and dosing.

• Custom Assay Development

Tailored assays to study specific receptor-ligand interactions, including rare and novel targets.

• High-Throughput Screening

Capabilities for screening large numbers of samples efficiently, ideal for drug development studies.

Advantages of Services Using Flow Cytometry Systems

• High Sensitivity and Specificity

Our flow cytometry systems provide accurate detection of receptor occupancy, even at low expression levels.

• Quantitative Analysis

Enables precise quantification of receptor-ligand interactions, providing critical data for drug development.

• Customizable Protocols

Flexible assay design to meet the specific needs of your research project.

• High Throughput

High-throughput analysis for the rapid processing of large sample numbers without compromising on data quality.

Our Equipment

BD FACSymphony A5

The BD FACSymphony A5 is a high-parameter flow cytometer equipped with five lasers and capable of detecting up to 28 colors. It offers unparalleled sensitivity and resolution, making it ideal for complex receptor occupancy studies.

Cytek Aurora Spectral Cytometer

The Cytek Aurora is a spectral flow cytometer that utilizes full-spectrum analysis, enabling the detection of highly overlapping fluorophores. It is particularly useful for multiplexed receptor occupancy assays.

BD FACSAria Fusion

The BD FACSAria Fusion is a high-speed cell sorter and analyzer that offers precise control over cell sorting and receptor occupancy measurements, ensuring accurate and reproducible results.

LSRFortessa X-20

The LSRFortessa X-20 is a versatile flow cytometer that supports up to five lasers and 20 parameters, making it well-suited for detailed receptor occupancy studies across various cell types.

STEMart provides high-quality flow cytometry services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our flow cytometry services and how we can help you achieve your research goals.