Macromolecular Structure Determination Service Based on 700 MHz Spectrometer

STEMart offers a specialized Macromolecular Structure Determination Service using cutting-edge 700 MHz spectrometers, including the Bruker Avance III 700 MHz and Bruker Avance NEO 700 MHz with Cryoprobe. These advanced instruments play a pivotal role in our laboratory by enabling high-resolution analysis of complex macromolecules such as proteins, nucleic acids, and polysaccharides. With enhanced sensitivity and resolution, our 700 MHz spectrometers are ideal for structural biology applications, allowing researchers to obtain precise molecular information even for large biomolecules.

The 700 MHz NMR technology at STEMart is based on nuclear magnetic resonance principles, which detect interactions between atomic nuclei in macromolecules. By using specialized techniques like multi-dimensional and heteronuclear correlation spectroscopy, our instruments provide in-depth structural data. This technology is widely applied in fields such as biochemistry, molecular biology, and pharmacology, supporting studies that require detailed analysis of biomolecular interactions, conformational changes, and complex assembly structures.

Leveraging our advanced 700 MHz NMR spectrometers, STEMart offers a comprehensive range of services tailored to the structural determination of macromolecules. Our services encompass 3D structure elucidation, interaction studies, and conformational analysis, providing researchers with critical data for drug discovery, enzyme studies, and biomolecular research.

What We Offer

• 3D Structural Elucidation of Macromolecules

Our 3D NMR analysis delivers high-resolution structural data, essential for understanding the detailed configuration of complex biomolecules such as proteins and nucleic acids.

• Protein-Ligand Interaction Studies

Comprehensive NMR services to study the binding interactions between proteins and ligands, supporting drug discovery and pharmacological research.

• Conformational Analysis of Biomolecules

Detailed analysis of macromolecular conformational states, essential for understanding dynamic structures and biological functions in natural and engineered biomolecules.

• Nucleic Acid Structure Analysis

High-sensitivity NMR studies for elucidating the structural intricacies of nucleic acids, supporting research in genetics, molecular biology, and therapeutic design.

• Multidimensional NMR for Complex Assemblies

Advanced multidimensional NMR techniques to examine large macromolecular assemblies, enabling precise insights into complex biological structures.

Why Choose Us

• Superior Sensitivity and Resolution

Our 700 MHz NMR systems provide enhanced sensitivity and spectral resolution, essential for detecting minute details in large biomolecules.

• Experienced Structural Biology Team

Our team of structural biology experts ensures reliable data interpretation, helping to advance research in biomolecular structure and function.

• Versatile Macromolecular Applications

Our services support a broad range of macromolecular research, from enzyme structure studies to protein-drug interactions, making us a versatile research partner.

• High-Quality and Fast Turnaround

We prioritize accuracy and efficiency, providing dependable results with a swift turnaround to meet the demands of critical research timelines.

Our Resources

Bruker Avance III 700 MHz NMR

This high-performance 700 MHz spectrometer from Bruker is optimized for macromolecular studies. Equipped with advanced probe technology, it provides high-resolution data essential for complex biomolecular analysis, supporting various applications in structural and molecular biology.

Bruker Avance NEO 700 MHz with Cryoprobe

The Bruker Avance NEO 700 MHz system features a Cryoprobe, enhancing sensitivity for detecting weak signals in large biomolecules. Its capabilities in multidimensional NMR make it ideal for studying macromolecular interactions and structural configurations at the atomic level.

STEMart provides high-quality NMR services tailored to meet the specific needs of our clients. Our experienced specialists use advanced equipment and follow strict quality control measures to ensure accurate and reliable results. Contact us to learn more about our NMR services and how we can help you achieve your research goals.