Tumor Mouse Model Service Based on Orthotopic and Subcutaneous Injection Techniques

STEMart provides a comprehensive Tumor Mouse Model Service utilizing orthotopic and subcutaneous injection techniques to create reliable in vivo models for cancer research. These techniques allow us to establish tumors in either the tissue of origin (orthotopic) or under the skin (subcutaneous), providing robust platforms for studying tumor biology, metastasis, and therapeutic responses. Our laboratory is equipped with advanced tools that enable precise cell injection and tumor monitoring, ensuring reproducibility and accuracy in all studies.

Orthotopic injection places cancer cells in the organ or tissue from which the cancer originated, providing a more physiologically relevant environment for studying tumor growth and metastasis. Subcutaneous injection, on the other hand, involves implanting cancer cells under the skin, which allows for easier tumor monitoring and measurement. Both methods are widely used in oncology research, drug development, and therapeutic testing due to their flexibility and applicability across various cancer types.

Leveraging our expertise in these injection techniques and our advanced imaging systems, we offer a broad range of tumor model services that support cancer biology research, drug discovery, and therapeutic validation. Whether you are exploring tumor progression or testing anti-cancer compounds, our models provide a reliable and reproducible foundation for your research.

What We Offer

• Orthotopic Tumor Model Service

Creation of tumor models by injecting cancer cells directly into the organ of origin, providing a more realistic environment for tumor growth and metastasis studies.

• Subcutaneous Tumor Model Service

Establishment of subcutaneous tumors by injecting cancer cells under the skin for easier tumor monitoring and treatment assessment.

• Metastasis Monitoring Service Based on Orthotopic Models

Tracking and studying tumor metastasis using orthotopic models that mimic the natural progression of cancer in its primary environment.

• Drug Efficacy Testing in Tumor Models

Preclinical testing of therapeutic compounds in orthotopic and subcutaneous tumor models to evaluate their efficacy in reducing tumor size or preventing metastasis.

• Pharmacokinetics and Toxicity Studies

Analysis of drug distribution, metabolism, and potential toxicity in tumor-bearing mice to ensure both safety and efficacy of cancer therapies.

Why Choose Us

• Physiologically Relevant Models

Our orthotopic models provide a realistic tumor environment, allowing for more accurate studies of tumor behavior and therapeutic response.

• Precision Injection Techniques

Using advanced injection systems, we ensure precise delivery of cancer cells into the desired site, resulting in consistent and reliable tumor models.

• Comprehensive Tumor Monitoring

Our cutting-edge imaging technologies allow for real-time, non-invasive monitoring of tumor growth and metastasis, providing detailed insights into tumor dynamics.

• Tailored Models for Specific Research Needs

We offer customized tumor model solutions to meet the specific needs of your research, including drug testing, biomarker discovery, and mechanistic studies.

Our Resources

Orthotopic Injection System (Harvard Apparatus PHD Ultra Syringe Pump)

This precision syringe pump ensures accurate and consistent delivery of cancer cells into the organ of interest, allowing for the reliable generation of orthotopic tumor models.

Subcutaneous Injection Platform (Hamilton Microliter Syringe)

Our Hamilton Microliter Syringe allows for precise subcutaneous injections, providing consistent tumor formation for easy monitoring and therapeutic testing.

In Vivo Imaging System (PerkinElmer IVIS Spectrum)

The PerkinElmer IVIS Spectrum enables non-invasive, real-time imaging of tumors, providing essential data on tumor progression and metastasis in live animals.

STEMart provides high-quality animal model services tailored to meet the specific needs of our clients. Our team of experienced specialists utilizes cutting-edge equipment and adheres to rigorous quality control protocols, ensuring precise and dependable results. Contact us to learn more about our animal model services and how we can help you achieve your research goals.